1901 Nonselective Cation Channels: Pharmacology, Physiology and Biophysics (Experientia Supplementum)
Nonselective Cation Channels: Pharmacology, Physiology and Biophysics (Experientia Supplementum)
Siemen , Hescheler
ハードカバー: 316ページ
Birkhaeuser Basel; 1版 (1993/10/1)
言語 英語
ISBN: 3764328886
In 1981, Neher and Sakmann published a pioneering paper describing the patch clamp method for measuring the currents slowing through individual ton channels. Apart from channels which are selective for a single species of ion, numerous 'nonselective channels' have been found since then, which are activated by various agonists and differ in selectivity and amino acid sequence. Today it is widely acknowledged that these channels belong to the most important components of the cell membrane and fulfil a wide spectrum of different functions. Nonselective Cation Channels is the first book to report on the immense variety and diversity of non-specific ion channels, ranging from the nicotinic acetylcholine receptor to the gap junction channel. Written by recognised international experts, its coverage also includes the role of nonselective cation channels in cardiac and smooth muscle cell functions, and their importance in human platelets and endothelial cells. Sections on receptor-activated and mechanically sensitive cation channels are also included. Primarily intended for scientists in basic biomedical and biological research, including physiology / electrophysiology, neurophysiology, pharmacology, toxicology, biochemistry, biophysics. neurobiology, cell biology, molecular biology and zoology, this book will also be of interest to clinicians as well as graduate and postgraduate students.